Basic Information
| LncRNA/CircRNA Name | PCAT6 |
| Synonyms | NA |
| Region | GRCh38_1:202810954-202812156 |
| Ensemble | ENSG00000228288 |
| Refseq | NR_046325 |
| Regulatory Mechanism | Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Information of Cancer
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, Luciferase reporter assay, Western blot |
| Sample | CRC tissues and cell lines ( HCT116, HT-29, SW620, SW480, DLD-1, RKO, LoVo, CCD-112CoN, HEK293 ) |
| Expression Pattern | up-regulated |
| Function Description | herein, PCAT6 expression was abnormally upregulated in CRC tissues and cell lines, suggesting its potential role in CRC. |
| Pubmed ID | 30938104 |
| Year | 2019 |
| Title | Long non-coding RNA PCAT6 targets miR-204 to modulate the chemoresistance of colorectal cancer cells to 5-fluorouracil-based treatment through HMGA2 signaling. |
External Links
| Links for PCAT6 | GenBank HGNC Noncode |
| Links for colorectal cancer | Omim Cosmic |