Basic Information
LncRNA/CircRNA Name | BCAR4 |
Synonyms | NA |
Region | GRCh38_16:11819829-11828845 |
Ensemble | ENSG00000262117 |
Refseq | NR_024049 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | non small cell lung cancer |
ICD-0-3 | C34 |
Methods | qPCR, Western blot |
Sample | non-small cell lung cancer tissues, cell lines (A549, SPC-A-1, PC-9, H157 and SK-MES-1) |
Expression Pattern | up-regulated |
Function Description | BCAR4 was higher in NSCLC tissues than that in cancer-adjacent tissues and was positively correlated with tumor size, clinical stage, and distant metastasis, suggesting that BCAR4 can be used as an independent predictor of prognosis. |
Pubmed ID | 28537678 |
Year | 2017 |
Title | LncRNA BCAR4 promotes proliferation, invasion and metastasis of non-small cell lung cancer cells by affecting epithelial-mesenchymal transition |
External Links
Links for BCAR4 | GenBank HGNC NONCODE |
Links for non small cell lung cancer | OMIM COSMIC |