Basic Information
| LncRNA/CircRNA Name | PCED1B-AS1 |
| Synonyms | PC-esterase domain containing 1B antisense RNA 1 |
| Region | GRCh38_12:47205898-47216456 |
| Ensemble | ENSG00000247774 |
| Refseq | NR_026544 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qRT-PCR, Luciferase reporter assay, RIP, Western blot assay |
| Sample | astrocyte (NHA) and glioma cells (LN229, U87, A172, and U251) |
| Expression Pattern | up-regulated |
| Function Description | Loss-of-function experiments depicted that the proliferation ability was restrained and apoptosis ability was induced in glioma cells by PCED1B-AS1 silencing and this phenomenon was also observed when PCED1B was knocked down. |
| Pubmed ID | 31680313 |
| Year | 2020 |
| Title | LncRNA PCED1B-AS1 Activates the Proliferation and Restricts the Apoptosis of Glioma Through Cooperating With miR-194-5p/PCED1B Axis |
External Links
| Links for PCED1B-AS1 | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |