Basic Information
| LncRNA/CircRNA Name | PCAT19 |
| Synonyms | prostate cancer associated transcript 19 |
| Region | GRCh38_19:41454169-41500649 |
| Ensemble | ENSG00000267107 |
| Refseq | NR_040109 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | RT-qPCR, Western blotting |
| Sample | NSCLC and adjacent normal tissue samples,H1993 human NSCLC cell line |
| Expression Pattern | up-regulated |
| Function Description | PCAT19 expression was upregulated in NSCLC tissues and also predicted poor patient survival rate.PCAT19 silencing was associated with the decreased proliferation rate of NSCLC cells, while PCAT19 overexpression led to increased proliferation. |
| Pubmed ID | 31819778 |
| Year | 2019 |
| Title | lncRNA PCAT19 Negatively Regulates p53 in Non-Small Cell Lung Cancer |
External Links
| Links for PCAT19 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |