Basic Information
| LncRNA/CircRNA Name | PCAT1 |
| Synonyms | LPCAT1, AGPAT10, AGPAT9, AYTL2, LPCAT-1, PFAAP3, lpcat, lysoPAFAT, PCAT-1 |
| Region | GRCh38_8:126556323-127419050 |
| Ensemble | ENSG00000253438 |
| Refseq | NR_045262 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | Microarray, qPCR etc. |
| Sample | CRC tissues |
| Expression Pattern | up-regulated |
| Function Description | The expression of all 18 candidate lncRNAs was evaluated by RT-qPCR, using 80 pairs of CRC and control tissue samples. Among these, eight lncRNAs (MALAT-1, NR_029373, NR_046321, NR_034119, GAS5, BANCR, NR_026817 and PCAT-1) were found significantly dysregulated in CRC tumor tissues compared with controls. |
| Pubmed ID | 27591862 |
| Year | 2016 |
| Title | Identification of long noncoding RNAs as potential novel diagnosis and prognosis biomarkers in colorectal cancer. |
External Links
| Links for PCAT1 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |