Basic Information
| LncRNA/CircRNA Name | BCAR4 |
| Synonyms | NA |
| Region | GRCh38_16:11819829-11828845 |
| Ensemble | ENSG00000262117 |
| Refseq | NR_024049 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | Western blot |
| Sample | Sgastric cancer7901, drug-resistant cell lines. |
| Expression Pattern | up-regulated |
| Function Description | In this research, we investigated whether lncRNAs have relations with drug resistance in gastric cancer to find new potential targets for therapy, which can increase the survival time of the drug-resistant gastric patient.Gastric cancer is a common malignancy with increasing worldwide incidence, and chemotherapeutic drugs for gastric cancer are not effective. Long non-coding RNA (lncRNA) has been proved to be important in different cancer progression. In this research, we investigated whether lncRNAs have relations with drug resistance in gastric cancer to find new potential targets for therapy, which can increase the survival. |
| Pubmed ID | 29028095 |
| Year | 2017 |
| Title | BCAR4 increase cisplatin resistance and predicted poor survival in gastric cancer patients. |
External Links
| Links for BCAR4 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |