Basic Information
LncRNA/CircRNA Name | PCAT1 |
Synonyms | LPCAT1, AGPAT10, AGPAT9, AYTL2, LPCAT-1, PFAAP3, lpcat, lysoPAFAT, PCAT-1 |
Region | GRCh38_8:126556323-127419050 |
Ensemble | ENSG00000253438 |
Refseq | NR_045262 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | gastric cancer |
ICD-0-3 | C16 |
Methods | qPCR |
Sample | All cell lines (AGS, Mgastric cancer-803, Bgastric cancer-823, GES-1, MKN-45) |
Expression Pattern | up-regulated |
Function Description | Our data suggested that PCAT-1 could play an oncogenic role in gastric cancer progression. Silencing PCAT-1 is a potential novel therapeutic approach for gastric cancer.Over-expression of PCAT-1 was correlated with poor overall survival in gastric cancer patients |
Pubmed ID | 28571676 |
Year | 2017 |
Title | Long non-coding RNA PCAT-1 over-expression promotes proliferation and metastasis in gastric cancer cells through regulating CDKN1A. |
External Links
Links for PCAT1 | GenBank HGNC NONCODE |
Links for gastric cancer | OMIM COSMIC |