Basic Information
| LncRNA/CircRNA Name | PCA3 |
| Synonyms | PCA3, DD3, NCRNA00019, PCAT3 |
| Region | GRCh38_9:76691980-76863307 |
| Ensemble | ENSG00000225937 |
| Refseq | NR_015342 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | prostate cancer |
| ICD-0-3 | C61.9 |
| Methods | qPCR etc. |
| Sample | prostate cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | It was found that the levels of the mRNA expression of DD3(PCA3) were significantly higher in patients with PCa than in patients with benign prostatic hyperplasia. DD3PCA3 appears to be a promising marker for early detection of PCa and also for differential diagnosis between patients with benign prostate hyperplasia and those with PCa. |
| Pubmed ID | 20332487 |
| Year | 2010 |
| Title | Differential display code 3 (DD3/PCA3) in prostate cancer diagnosis. |
External Links
| Links for PCA3 | GenBank HGNC NONCODE |
| Links for prostate cancer | OMIM COSMIC |