Basic Information
| LncRNA/CircRNA Name | PCA3 |
| Synonyms | PCA3, DD3, NCRNA00019, PCAT3 |
| Region | GRCh38_9:76691980-76863307 |
| Ensemble | ENSG00000225937 |
| Refseq | NR_015342 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | prostate cancer |
| ICD-0-3 | C61.9 |
| Methods | qPCR |
| Sample | prostate cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | The data showed that the pair of primers for amplifying exon 3-4 fragment of PCA3 generated the highest score of the ratio in either cancerous prostate tissue or control tissue when compared with using other two pairs of primers to amplify two of other fragments accordingly, and it also showed significant difference between the CaP group and the control group |
| Pubmed ID | 28938580 |
| Year | 2017 |
| Title | Diagnostic significance of urinary long non-coding PCA3 RNA in prostate cancer |
External Links
| Links for PCA3 | GenBank HGNC NONCODE |
| Links for prostate cancer | OMIM COSMIC |