Basic Information
| LncRNA/CircRNA Name | PCA3 |
| Synonyms | PCA3, DD3, NCRNA00019, PCAT3 |
| Region | GRCh38_9:76691980-76863307 |
| Ensemble | ENSG00000225937 |
| Refseq | NR_015342 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | chronic myeloid leukemia |
| ICD-0-3 | NA |
| Methods | qPCR, other |
| Sample | K562 cell line, blood |
| Expression Pattern | up-regulated |
| Function Description | The results showed that PCA3 has expression in both normal and leukemic white blood cells. The data also revealed higher expression of PCA3 in leukemic patients, compared to the normal counterpart (P < 0.05)s of molecular pathways related to PCA3 which could help achieve better treatment. |
| Pubmed ID | 30197352 |
| Year | 2018 |
| Title | Gene Expression Analysis of Noncoding PCA3 Gene in Patients With Chronic Myeloid Leukemia |
External Links
| Links for PCA3 | GenBank HGNC NONCODE |
| Links for chronic myeloid leukemia | OMIM COSMIC |