Basic Information
| LncRNA/CircRNA Name | PANDAR |
| Synonyms | PANDAR, PANDA |
| Region | GRCh38_6:36673621-36675126 |
| Ensemble | ENSG00000281450 |
| Refseq | NR_109836 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, RNAi, MTT assay etc. |
| Sample | CRC tissues, cell lines (HCT116, HT29, SW480, DLD-1) |
| Expression Pattern | up-regulated |
| Function Description | The expression level of PANDAR was higher in CRC tissues and cells compared with adjacent nontumor tissues and normal colonic cell line NCM460. PANDAR expression was significantly correlated with local invasion, lymph node metastasis and TNM stage. Furthermore, PANDAR knockdown significantly inhibited cell proliferation, cycle progression, migration and invasion of CRC in vitro. |
| Pubmed ID | 28106228 |
| Year | 2017 |
| Title | Expression of long non-coding RNA PANDAR and its prognostic value in colorectal cancer patients. |
External Links
| Links for PANDAR | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |