Basic Information
LncRNA/CircRNA Name | PANDAR |
Synonyms | PANDAR, PANDA |
Region | GRCh38_6:36673621-36675126 |
Ensemble | ENSG00000281450 |
Refseq | NR_109836 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | hepatocellular carcinoma |
ICD-0-3 | C22.0 |
Methods | qPCR, RNAi etc. |
Sample | HCC tissues, cell lines (HCCLM3, Hep3B, HepG2) |
Expression Pattern | up-regulated |
Function Description | PANDAR was overexpressed in HCC tissues and cell lines. Moreover, its expression level was significantly correlated with liver cirrhosis, HBsAg, AFP, tumor nodule, vascular invasion and TNM stage. PANDAR overexpression was associated with poorer survival and shorter recurrence and served as an independent prognostic marker of patients with HCC. |
Pubmed ID | 26054684 |
Year | 2015 |
Title | Long non-coding RNA PANDAR correlates with poor prognosis and promotes tumorigenesis in hepatocellular carcinoma. |
External Links
Links for PANDAR | GenBank HGNC NONCODE |
Links for hepatocellular carcinoma | OMIM COSMIC |