Basic Information
| LncRNA/CircRNA Name | OVAL |
| Synonyms | OVAAL, LINC01131, OVAL |
| Region | GRCh38_1:180558976-180566518 |
| Ensemble | ENSG00000236719 |
| Refseq | NR_125716 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | RNA-seq, qPCR etc. |
| Sample | ovarian cancer tissues |
| Expression Pattern | down-regulated |
| Function Description | OVAL expression was low or absent in both normal fallopian tube and in the majority of tumors, including most cases with wide 1q amplification. However, focal amplification of the OVAL locus coincided strikingly with OVAL transcriptional activation. |
| Pubmed ID | 24265805 |
| Year | 2013 |
| Title | Comprehensive analysis of long non-coding RNAs in ovarian cancer reveals global patterns and targeted DNA amplification. |
External Links
| Links for OVAL | GenBank HGNC NONCODE |
| Links for ovarian cancer | OMIM COSMIC |