Basic Information
LncRNA/CircRNA Name | OIP5-AS1 |
Synonyms | OIP5-AS1, cyrano, linc-OIP5 |
Region | GRCh38_15:41283990-41309737 |
Ensemble | ENSG00000247556 |
Refseq | NR_026757 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | cervical cancer |
ICD-0-3 | C53 |
Methods | qPCR, RIP etc. |
Sample | cell line (HeLa) |
Expression Pattern | differential expression |
Function Description | To begin examining the function of lncRNA OIP5-AS1, we silenced it in HeLa cells by transfecting a pool of siRNAs directed at OIP5-AS1 and studied the ensuing changes in cell numbers. Silencing OIP5-AS1 promoted cell proliferation. |
Pubmed ID | 26819413 |
Year | 2016 |
Title | LncRNA OIP5-AS1/cyrano sponges RNA-binding protein HuR. |
External Links
Links for OIP5-AS1 | GenBank HGNC NONCODE |
Links for cervical cancer | OMIM COSMIC |