Basic Information
| LncRNA/CircRNA Name | OIP5-AS1 |
| Synonyms | NA |
| Region | GRCh38_15:41283990-41309737 |
| Ensemble | ENSG00000247556 |
| Refseq | NR_026757 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hemangioma |
| ICD-0-3 | NA |
| Methods | qRT-PCR , RIP , Western blot , in vitro knockdown etc. |
| Sample | HA tissues and normal skin tissues ,Hemangioma endothelial cells (HemECs)? |
| Expression Pattern | up-regulated |
| Function Description | OIP5-AS1 was overexpressed in both hemangioma tissues and HemECs cells.OIP5-AS1 knockdown suppressed the proliferation, migration, and invasion of HemECs cell, while overexpression of OIP5-AS1 had opposite effects.OIP5-AS1 acted as a ceRNA through binding with miR-195-5p to upregulate NOB1 in HemECs. |
| Pubmed ID | 31068824 |
| Year | 2019 |
| Title | LncRNA OIP5-AS1 Promotes the Proliferation of Hemangioma Vascular Endothelial Cells via Regulating miR-195-5p/NOB1 Axis |
External Links
| Links for OIP5-AS1 | GenBank HGNC NONCODE |
| Links for hemangioma | OMIM COSMIC |