Basic Information
| LncRNA/CircRNA Name | BC200 |
| Synonyms | BCYRN1, BC200, BC200a, LINC00004, NCRNA00004 |
| Region | GRCh38_2:47335315-47335514 |
| Ensemble | ENSG00000236824 |
| Refseq | NR_001568 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qPCR etc. |
| Sample | cell lines (U251, U87) |
| Expression Pattern | down-regulated |
| Function Description | MEG3 and ST7OT1 are up-regulated in both cell lines under apoptosis induced using both agents. The induction of GAS5 is only clearly detected during DOX-induced apoptosis, whereas the up-regulation of neat1 and MIR155HG is only found during RES-induced apoptosis in both cell lines. However, TUG1, BC200 and MIR155HG are down regulated when necrosis is induced using a high dose of DOX in both cell lines. |
| Pubmed ID | 25645334 |
| Year | 2015 |
| Title | Altered expression of long non-coding RNAs during genotoxic stress-induced cell death in human glioma cells |
External Links
| Links for BC200 | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |