Basic Information
LncRNA/CircRNA Name | NR2F2-AS1 |
Synonyms | NA |
Region | GRCh38_15:96110040-96327361 |
Ensemble | ENSG00000247809 |
Refseq | XR_109225 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | clear cell renal cell carcinoma |
ICD-0-3 | C64.9 |
Methods | RT-qPCR |
Sample | ccRCC tissues,cell lines |
Expression Pattern | up-regulated |
Function Description | NR2F2-AS1 and Rac1 overexpression resulted in the increased ccRCC cell stemness, whereas NR2F2-AS1 and Rac1 siRNA silencing played an opposite role. Rac1 overexpression inhibited the role of NR2F2-AS1 siRNA silencing. |
Pubmed ID | 32109138 |
Year | 2020 |
Title | LncRNA NR2F2-AS1 Upregulates Rac1 to Increase Cancer Stemness in Clear Cell Renal Cell Carcinoma |
External Links
Links for NR2F2-AS1 | GenBank HGNC NONCODE |
Links for clear cell renal cell carcinoma | OMIM COSMIC |