Basic Information
| LncRNA/CircRNA Name | BC200 |
| Synonyms | BCYRN1, BC200, BC200a, LINC00004, NCRNA00004 |
| Region | GRCh38_2:47335315-47335514 |
| Ensemble | ENSG00000236824 |
| Refseq | NR_001568 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | esophageal squamous cell carcinoma |
| ICD-0-3 | NA |
| Methods | qPCR etc. |
| Sample | ESCC tissues |
| Expression Pattern | up-regulated |
| Function Description | We found that the relative expression of BC200 was significantly higher in ESCC tissues compared with adjacent normal tissue samples. But the expression of BC200 were not related to clinical-pathological features, such as age, TNM stages, and histological grade. Kaplan-Meier analysis showed that high expression levels of BC200 were correlated with poor prognosis in ESCC patients. Patients with a high level of BC200 had a shorter disease-free survival and overall survival than those with low BC200 expression. On multivariate analysis, the hazard ratio (HR) of BC200 expression was 2.17 for disease-free survival and 2.24 for overall survival |
| Pubmed ID | 27143917 |
| Year | 2016 |
| Title | BC200 LncRNA a potential predictive marker of poor prognosis in esophageal squamous cell carcinoma patients |
External Links
| Links for BC200 | GenBank HGNC NONCODE |
| Links for esophageal squamous cell carcinoma | OMIM COSMIC |