Basic Information
| LncRNA/CircRNA Name | NR_036575.1 |
| Synonyms | LOC729966, DPDE1, PDE4C |
| Region | GRCh38_19:18208652-18248200 |
| Ensemble | ENSG00000105650 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | papillary thyroid cancer |
| ICD-0-3 | NA |
| Methods | qPCR, RNAi, Cell proliferation assay, Cell migration assay etc. |
| Sample | PTC tissues, cell lines (Nthy-ori 3-1, TPC1, IHH-4) |
| Expression Pattern | up-regulated |
| Function Description | The expression levels of the lncRNA NR_036575.1 were significantly higher in PTC tissues than in adjacent non-cancerous tissues. High NR_036575.1 expression was associated with extrathyroidal extension and tumour size. NR_036575.1 knock-down significantly inhibited the proliferation and migration of TPC1 cells. |
| Pubmed ID | 27510368 |
| Year | 2016 |
| Title | Overexpression of long non-coding RNA NR_036575.1 contributes to the proliferation and migration of papillary thyroid cancer. |
External Links
| Links for NR_036575.1 | GenBank HGNC NONCODE |
| Links for papillary thyroid cancer | OMIM COSMIC |