Basic Information
| LncRNA/CircRNA Name | BC200 |
| Synonyms | brain cytoplasmic 200 |
| Region | NA |
| Ensemble | ENSG00000236824 |
| Refseq | NR_001568 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | RT-qPCR, Western blot analysis |
| Sample | HCC tissue,HepG2 cells |
| Expression Pattern | up-regulated |
| Function Description | BC200 expression level was higher in hepatocellular carcinoma (HCC) tissues than that in adjacent tissues.BC200 affected the proliferation and migration of HepG2 cells.BC200 KO cells exhibited a reduced protein expression level of Bax protein and an increased protein expression level of Bcl-xL. Conversely, BC200 overexpression reduced the expression of Bcl-xL protein and increased the expression of Bax protein. |
| Pubmed ID | 31894342 |
| Year | 2020 |
| Title | Effect of lncRNA-BC200 on Proliferation and Migration of Liver Cancer Cells in Vitro and in Vivo |
External Links
| Links for BC200 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |