Basic Information
| LncRNA/CircRNA Name | BC050642 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | osteosarcoma |
| ICD-0-3 | NA |
| Methods | qPCR |
| Sample | Human osteosarcoma cell lines U2OS and normal osteoblastic cell line hFOB1.19, Osteosarcoma tissues, paired adjacent tissues and healthy tissues, Osteosarcoma tissues, paired adjacent tissues and healthy tissues |
| Expression Pattern | up-regulated |
| Function Description | BC050642 levels showed distinctive increases in osteosarcoma tissues and cell lines compared with controls. And c-myc expression was down-regulated in osteosarcoma. There was a negative correlation between the expressions of BC050642 and c-myc. BC050642 expression was proved to be significantly correlated with Ennking and histological type. Up-regulated BC050642 could promote cell proliferation, induce colony formation and meanwhile inhibit cell apoptosis. |
| Pubmed ID | 31397185 |
| Year | 2019 |
| Title | The Potential Value of lncRNA-BC050642 in Osteosarcoma Origination and Outcomes |
External Links
| Links for BC050642 | GenBank HGNC NONCODE |
| Links for osteosarcoma | OMIM COSMIC |