Basic Information
| LncRNA/CircRNA Name | NKILA |
| Synonyms | NA |
| Region | GRCh38_20:57710183-57712780 |
| Ensemble | ENSG00000278709 |
| Refseq | NR_131157 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cervical squamous cell carcinoma |
| ICD-0-3 | C53 |
| Methods | RT-qPCR |
| Sample | Blood samples,CSCC cell lines SiHa (HPV-positive) and C33A (HPV-negative) |
| Expression Pattern | down-regulated |
| Function Description | lncRNA NKILA is downregulated in CSCC. Overexpression of lncRNA NKILA may inhibit proliferation and promote apoptosis of CSCC cells by downregulating miRNA-21. |
| Pubmed ID | 31950510 |
| Year | 2020 |
| Title | LncRNA NKILA Inhibits the Proliferation and Promotes the Apoptosis of CSCC Cells by Downregulating miRNA-21 |
External Links
| Links for NKILA | GenBank HGNC NONCODE |
| Links for cervical squamous cell carcinoma | OMIM COSMIC |