Basic Information
| LncRNA/CircRNA Name | NHEG1 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | neuroblastoma |
| ICD-0-3 | NA |
| Methods | RT-PCR, Western blot |
| Sample | NB tissues, cell lines |
| Expression Pattern | up-regulated |
| Function Description | lncRNA NHEG1 exhibits oncogenic activity that affects NB progression via stabilizing the DDX5 protein, which might serve as a potential therapeutic target for NB. |
| Pubmed ID | 31982037 |
| Year | 2020 |
| Title | Long Noncoding RNA NHEG1 Drives b-Catenin Transactivation and Neuroblastoma Progression through Interacting with DDX5 |
External Links
| Links for NHEG1 | GenBank HGNC NONCODE |
| Links for neuroblastoma | OMIM COSMIC |