Basic Information
| LncRNA/CircRNA Name | NEAT1 |
| Synonyms | NEAT1, LINC00084, NCRNA00084, TncRNA, VINC |
| Region | GRCh38_11:65422774-65445540 |
| Ensemble | ENSG00000245532 |
| Refseq | NR_028272 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cholangiocarcinoma |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot, RIP, ChIP, etc. |
| Sample | The human cholangiocacinoma cell lines (QBC939, RBE, HuCCT1, TFK-1). normal biliary epithelium cell line HIBEpic. CCA tumors, adjacent non-tumor tissue |
| Expression Pattern | up-regulated |
| Function Description | These findings indicate that NEAT1 exerts oncogenic effects in CCA. We postulate that NEAT1 is a potentially useful diagnostic and therapeutic target for CCA. CCA is aggressive cancer with a median survival of fewer than 24 months after diagnosis. |
| Pubmed ID | 29970216 |
| Year | 2018 |
| Title | Long Noncoding RNA NEAT1 Promotes Growth and Metastasis of Cholangiocarcinoma Cells. |
External Links
| Links for NEAT1 | GenBank HGNC NONCODE |
| Links for cholangiocarcinoma | OMIM COSMIC |