Basic Information
| LncRNA/CircRNA Name | NEAT1 |
| Synonyms | NA |
| Region | GRCh38_11:65422774-65445540 |
| Ensemble | ENSG00000245532 |
| Refseq | NR_028272 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | osteosarcoma |
| ICD-0-3 | NA |
| Methods | qPCR |
| Sample | Osteosarcoma tissues, cell line U-2 OS |
| Expression Pattern | up-regulated |
| Function Description | NEAT1 was over-expressed in osteosarcoma tissues compared with adjacent non-tumor tissues. In addition, knockdown of NEAT1 expression could suppress cell proliferation, migration and invasion in vitro. |
| Pubmed ID | 30123061 |
| Year | 2018 |
| Title | Long non-coding RNA NEAT1 promotes proliferation, migration and invasion of human osteosarcoma cells. |
External Links
| Links for NEAT1 | GenBank HGNC NONCODE |
| Links for osteosarcoma | OMIM COSMIC |