Basic Information
| LncRNA/CircRNA Name | NEAT1 |
| Synonyms | NA |
| Region | GRCh38_11:65422774-65445540 |
| Ensemble | ENSG00000245532 |
| Refseq | NR_028272 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | RNA-seq |
| Sample | HCC tissues |
| Expression Pattern | up-regulated |
| Function Description | In the present research, the level of NEAT1 was found to be upregulated in HCC by The Cancer Genome Atlas. In addition, NEAT1 expression is negatively correlated with the survival rate in HCC. |
| Pubmed ID | 31549407 |
| Year | 2019 |
| Title | LncRNA NEAT1 promotes autophagy via regulating miR-204/ATG3 and enhanced cell resistance to sorafenib in hepatocellular carcinoma. |
External Links
| Links for NEAT1 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |