Basic Information
| LncRNA/CircRNA Name | NEAT1 |
| Synonyms | NA |
| Region | GRCh38_11:65422774-65445540 |
| Ensemble | ENSG00000245532 |
| Refseq | NR_028272 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | RT-qPCR, Western blot |
| Sample | CRC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | lncRNA NEAT1 was found to be upregulated in CRC cell lines, promoting CRC cell proliferation, migration, and invasion through regulating the miR-205-5p/VEGFA signaling pathway. |
| Pubmed ID | 32065361 |
| Year | 2019 |
| Title | Long non-coding RNA NEAT1 promotes colorectal cancer progression by?regulating miR-205-5p/VEGFA axis |
External Links
| Links for NEAT1 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |