Basic Information
LncRNA/CircRNA Name | NEAT1 |
Synonyms | NA |
Region | GRCh38_11:65422774-65445540 |
Ensemble | ENSG00000245532 |
Refseq | NR_028272 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | cervical cancer |
ICD-0-3 | C53 |
Methods | qRT-PCR, Western blot |
Sample | cervical cancer tissues and cell lines |
Expression Pattern | up-regulated |
Function Description | NEAT1 directly repressed miR-361 expression and played an oncogenic role in CC cell invasion and sphere formation. |
Pubmed ID | 32151082 |
Year | 2020 |
Title | MicroRNA-361-Mediated Inhibition of HSP90 Expression and EMT in Cervical Cancer Is Counteracted by Oncogenic lncRNA NEAT1 |
External Links
Links for NEAT1 | GenBank HGNC NONCODE |
Links for cervical cancer | OMIM COSMIC |