Basic Information
| LncRNA/CircRNA Name | ncRuPAR |
| Synonyms | NCRUPAR, NCRNA00193, ncR-uPAR |
| Region | NA |
| Ensemble | NA |
| Refseq | NR_028375 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR etc. |
| Sample | gastric cancer tissues |
| Expression Pattern | down-regulated |
| Function Description | The level of ncRuPAR in gastric cancer was low, and its expression level was associated with invasion depth, lymph node metastasis, distant metastasis, tumor size, and TNM stage. These findings indicate that ncRuPAR might be a potential marker for gastric cancer diagnosis. ncRuPAR might also be a tumor suppressor because it regulates the expression of PAR-1. |
| Pubmed ID | 24817013 |
| Year | 2014 |
| Title | ncRuPAR inhibits gastric cancer progression by down-regulating protease-activated receptor-1. |
External Links
| Links for ncRuPAR | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |