Basic Information
LncRNA/CircRNA Name | NCRNA00210 |
Synonyms | LINC00210, NCRNA00210 |
Region | GRCh38_1:217892900-217920804 |
Ensemble | ENSG00000231814 |
Refseq | NR_048550 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | non small cell lung cancer |
ICD-0-3 | C34 |
Methods | Microarray, qPCR, RNAi, Western blot etc. |
Sample | cell lines (A549, CDDP etc.) |
Expression Pattern | up-regulated |
Function Description | For lncRNA, the results showed that AK123263, CES1P1-001, RP3-508I15.14, AK126698, TP53TG1, and AC090952.4.1 decreased, whereas uc003bgl.1 and NCRNA00210 increased in A549/CDDP. Cisplatin resistance in non-small-cell lung cancer cells may relate to the changes in noncoding RNAs. Among these, AK126698 appears to confer cisplatin resistance by targeting the Wnt pathway. |
Pubmed ID | 23741487 |
Year | 2013 |
Title | The noncoding RNA expression profile and the effect of lncRNA AK126698 on cisplatin resistance in non-small-cell lung cancer cell. |
External Links
Links for NCRNA00210 | GenBank HGNC NONCODE |
Links for non small cell lung cancer | OMIM COSMIC |