Basic Information
| LncRNA/CircRNA Name | NCRNA00028 |
| Synonyms | LINC00028, C20orf93, NCRNA00028, dJ1093G12.6 |
| Region | GRCh38_20:31485778-31487574 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colon cancer |
| ICD-0-3 | C18 |
| Methods | Microarray, qPCR, RNA pull-down assay etc. |
| Sample | cell line (HCT-118) |
| Expression Pattern | down-regulated |
| Function Description | Quantitative RT-PCR analyses confirmed transcriptional silencing in HCT-116 cells and demethylation-associated reactivation in DKO cells for seven (70%) of the lncRNAs: TP53TG1, NCRNA00028, LOC157627, MIR155HG, WT1AS, C20orf200, and MYCNOS. |
| Pubmed ID | 27821766 |
| Year | 2016 |
| Title | Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer. |
External Links
| Links for NCRNA00028 | GenBank HGNC NONCODE |
| Links for colon cancer | OMIM COSMIC |