Basic Information
| LncRNA/CircRNA Name | NBAT1 |
| Synonyms | NBAT1, CASC14, NBAT-1 |
| Region | GRCh38_6:22134957-22147193 |
| Ensemble | ENSG00000260455 |
| Refseq | NR_034143 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | clear cell renal cell carcinoma |
| ICD-0-3 | C64.9 |
| Methods | qPCR, RNAi etc. |
| Sample | ccRCC tissues, cell lines (786-O, ACHN, Caki-1 etc.) |
| Expression Pattern | down-regulated |
| Function Description | NBAT-1 expression is significantly decreased in ccRCC tissues and renal cancer cells compared with adjacent normal tissues and normal human proximal tubule epithelial cell line HK-2, and its low level is associated with advanced features and poor prognosis. NBAT-1 is a novel molecular correlated with ccRCC progression and it may represent a prognostic biomarker and therapeutic target in renal cancer diagnosis and treatment. |
| Pubmed ID | 26097558 |
| Year | 2015 |
| Title | Decreased expression of long non-coding RNA NBAT-1 is associated with poor prognosis in patients with clear cell renal cell carcinoma. |
External Links
| Links for NBAT1 | GenBank HGNC NONCODE |
| Links for clear cell renal cell carcinoma | OMIM COSMIC |