Basic Information
LncRNA/CircRNA Name | NAMA |
Synonyms | NAMA |
Region | GRCh38_9:99355337-99377240 |
Ensemble | ENSG00000271086 |
Refseq | NR_102270 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | papillary thyroid cancer |
ICD-0-3 | NA |
Methods | qPCR, RNAi, Western blot, Northern blot etc. |
Sample | PTA tissues tissues, cell lines (NPA87, K1, K2 etc.) |
Expression Pattern | down-regulated |
Function Description | The downregulation of NAMA in PTCs with the BRAF*V600E mutation led us to test whether NAMA is regulated by the MAP kinase pathway. We suggest that NAMA is a noncoding RNA associated with growth arrest. |
Pubmed ID | 17415708 |
Year | 2007 |
Title | Identification of a novel noncoding RNA gene, NAMA, that is downregulated in papillary thyroid carcinoma with BRAF mutation and associated with growth arrest. |
External Links
Links for NAMA | GenBank HGNC NONCODE |
Links for papillary thyroid cancer | OMIM COSMIC |