Basic Information
| LncRNA/CircRNA Name | NALT1 |
| Synonyms | NA |
| Region | GRCh38_9:136546212-136549893 |
| Ensemble | ENSG00000237886 |
| Refseq | NR_121577 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | RT-PCR, Western blotting |
| Sample | gastric epithelial cell line GES-1 and human gastric cancer cell lines SGC-7901 and BGC-823,GC patient |
| Expression Pattern | up-regulated |
| Function Description | Pearson's correlation showed that blue module was correlated with tumor grade and survival. NALT1 was the hub-lncRNA of blue module and was an independent risk factor for GC prognosis. NALT1 was overexpressed in GC and its expression was closely related to invasion and metastasis. |
| Pubmed ID | 31802831 |
| Year | 2019 |
| Title | Long Noncoding RNA NALT1-induced Gastric Cancer Invasion and Metastasis via NOTCH Signaling Pathway |
External Links
| Links for NALT1 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |