Basic Information
| LncRNA/CircRNA Name | AC008392.1 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR |
| Sample | non small cell lung cancer tissues |
| Expression Pattern | differential expression |
| Function Description | The variant genotype of rs7248320 was significantly related to the risk of non-small-cell lung cancer (NSCLC). Individuals carrying homozygous GG genotype had decreased risk of NSCLC, compared with individuals carrying the homozygous wild AA genotype/heterozygote GA genotype . Moreover, in the subgroup of ages, there were statistically significant associations between rs7248320 and the risk of lung cancer and NSCLC in the population over 60 years of age. Compared with individuals carrying genotypes AA/GA, individuals with genotype GG had the lower risk of lung cancer and NSCLC. Compared with homozygote AA, the homozygote GG was associated with a decreased risk in NSCLC (OR =0.456, 95% CI =0.235-0.887, P=0.021). |
| Pubmed ID | 29881308 |
| Year | 2018 |
| Title | Polymorphism in lncRNA AC008392.1 and Its Interaction With Smoking on the Risk of Lung Cancer in a Chinese Population |
External Links
| Links for AC008392.1 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |