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Basic Information

Classification Information

Regulatory Mechanism		Biological Function		Clinical Application
TF		Immune		Survival
Enhancer		Apoptosis		Drug
Variant		Cell Growth		Circulating
MiRNA		EMT		Metastasis
Methylation		Coding Ability		Recurrence

Cancer&Entry Information

Cancer Name	bladder cancer
ICD-0-3	C67
Methods	qPCR, other
Sample	bladder cancer tissues and cell lines
Expression Pattern	up-regulated
Function Description	In addition, the results of fluorescence in situ hybridization analysis of bladder cancer cells and tissues demonstrated that lncRNA-n346372 is located in the cytoplasm, and the expression of lncRNA-n346372 in bladder cancer tissues was significantly increased compared with the paired normal tissues. Following a ?2 test with common clinical variables among the patients, the expression level of lncRNA-n346372 was demonstrated to be positively associated with advanced tumor stage and poor histological differentiation of bladder cancer. Kaplan-Meier survival analysis revealed that patients with high expression of n346372 were more likely to have a poor prognosis compared with patients with low n346372 expression. Finally, univariate and multivariate analyses indicated that the relative level of n346372, apart from tumor stage and histological grade, may serve as an independent prognostic factor of bladder cancer.
Pubmed ID	30365104
Year	2018
Title	Overexpression of Long Non-coding RNA n346372 in Bladder Cancer Tissues Is Associated With a Poor Prognosis

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