Basic Information
| LncRNA/CircRNA Name | MSC-AS1 |
| Synonyms | NA |
| Region | GRCh38_8:71828167-72118393 |
| Ensemble | ENSG00000235531 |
| Refseq | NR_033652 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | pancreatic cancer |
| ICD-0-3 | C25 |
| Methods | qPCR, Luciferase reporter assay, RIP |
| Sample | PDAC tissues, cell lines(PANC-1,BxPC-3) |
| Expression Pattern | up-regulated |
| Function Description | MSC-AS1 expression was upregulated in PDAC tissues. Higher MSC-AS1 expression was correlated with poorer prognosis in patients with PDAC. |
| Pubmed ID | 30915884 |
| Year | 2019 |
| Title | The role of lncRNA MSC-AS1/miR-29b-3p axis-mediated CDK14 modulation in pancreatic cancer proliferation and Gemcitabine-induced apoptosis. |
External Links
| Links for MSC-AS1 | GenBank HGNC NONCODE |
| Links for pancreatic cancer | OMIM COSMIC |