Basic Information
| LncRNA/CircRNA Name | MPRL |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | Cisplatin | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | tongue squamous cell carcinoma |
| ICD-0-3 | C02 |
| Methods | qPCR, Microarray, Luciferase reporter assay |
| Sample | TSCC tissues, cell lines |
| Expression Pattern | up-regulated |
| Function Description | We found that MPRL expression was significantly upregulated in TSCC cell lines treated with cisplatin and transactivated by E2F1. |
| Pubmed ID | 30885939 |
| Year | 2019 |
| Title | Long Noncoding RNA MPRL Promotes Mitochondrial Fission and Cisplatin Chemosensitivity via Disruption of Pre-miRNA Processing. |
External Links
| Links for MPRL | GenBank HGNC NONCODE |
| Links for tongue squamous cell carcinoma | OMIM COSMIC |