Basic Information
| LncRNA/CircRNA Name | MNX1-AS1 |
| Synonyms | MNX1-AS1, CCAT5 |
| Region | GRCh38_7:157010805-157016426 |
| Ensemble | ENSG00000243479 |
| Refseq | NR_038835 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | qPCR |
| Sample | epithelial ovarian cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | the levels of MNX1-AS1 were higher in EOC tissue than in matched normal tissues.MNX1-AS1 expression level was significantly positively correlated with FIGO stage, grade and distant metastasis.poorer progression-free survival and overall survival than those with low-MNX1-AS1 expression.FIGO stage,distant metastasis, and MNX1-AS1 expression were independent prognostic factors of both overall survival and progression-free survival for patients with EOC. |
| Pubmed ID | 29271994 |
| Year | 2017 |
| Title | Overexpression of lncRNA MNX1-AS1 is associated with poor clinical outcome in epithelial ovarian cancer. |
External Links
| Links for MNX1-AS1 | GenBank HGNC NONCODE |
| Links for ovarian cancer | OMIM COSMIC |