Basic Information
| LncRNA/CircRNA Name | MIR503HG |
| Synonyms | MIR503HG, H19X, MIR503HG2 |
| Region | GRCh38_X:134543337-134546632 |
| Ensemble | ENSG00000223749 |
| Refseq | NR_024607 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | Microarray, RIP etc. |
| Sample | hepatocellular carcinoma tissues, celllines (SMMC-7721 and Huh7) |
| Expression Pattern | up-regulated |
| Function Description | Expression level of miR503HG is significantly associated with the time to recurrence and overall survival and is an independent risk factor for recurrence and survival. Enhanced expression of miR503HG could noticeably inhibit HCC invasion and metastasis in vitro and in vivo. |
| Pubmed ID | 29774077 |
| Year | 2018 |
| Title | Long noncoding RNA miR503HG, a prognostic indicator, inhibits tumor metastasis by regulating the HNRNPA2B1/NF-kB pathway in hepatocellular carcinoma |
External Links
| Links for MIR503HG | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |