Basic Information
| LncRNA/CircRNA Name | MIR4435-2HG |
| Synonyms | NA |
| Region | GRCh38_2:111036776-111523376 |
| Ensemble | ENSG00000172965 |
| Refseq | NR_015395 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioblastoma |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot, luciferase reporter assay etc |
| Sample | GBM tissues as well as the adjacent normal tissues,cell lines (LN229, U87MG, U87 and U251) |
| Expression Pattern | up-regulated |
| Function Description | LncRNA MIR4435-2HG potentiates the proliferation and invasion of glioblastoma cells via modulating miR-1224-5p/TGFBR2 axis. |
| Pubmed ID | 32319715 |
| Year | 2020 |
| Title | LncRNA MIR4435-2HG potentiates the proliferation and invasion of glioblastoma cells via modulating miR-1224-5p/TGFBR2 axis |
External Links
| Links for MIR4435-2HG | GenBank HGNC NONCODE |
| Links for glioblastoma | OMIM COSMIC |