Basic Information
| LncRNA/CircRNA Name | miR143HG |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | endometrial cancer |
| ICD-0-3 | NA |
| Methods | qRT-PCR, Western blot |
| Sample | EC tissues,EC cell line HEC-1 |
| Expression Pattern | down-regulated |
| Function Description | the down-regulation of miR143HG in EC predicted poor survival.miR143HG over-expression led to the up-regulated p53.Cell apoptosis analysis showed that miR143HG and p53 over-expression led to an increased cell apoptotic rate.MiR143HG may up-regulate p53 in EC by sponging miR-125a to promote cancer cell apoptosis. |
| Pubmed ID | 31819644 |
| Year | 2019 |
| Title | LncRNA miR143HG Up-Regulates p53 In Endometrial Carcinoma By Sponging miR-125a |
External Links
| Links for miR143HG | GenBank HGNC NONCODE |
| Links for endometrial cancer | OMIM COSMIC |