Basic Information
| LncRNA/CircRNA Name | MIR100HG |
| Synonyms | NA |
| Region | GRCh38_11:122028327-122556721 |
| Ensemble | ENSG00000255248 |
| Refseq | NR_024430 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | laryngeal squamous cell cancer |
| ICD-0-3 | C32.3 |
| Methods | qRT-PCR etc. |
| Sample | tumor tissues and adjacent healthy tissues ,Human LSCC cell line UM-SCC-17A |
| Expression Pattern | up-regulated |
| Function Description | MIR100HG was upregulated, while miR-204-5p was downregulated in tumor tissues than in adjacent healthy tissues of laryngeal squamous cell carcinoma (LSCC) patients.Expression of MIR100HG was significantly affected by AJCC stage.MIR100HG promoted cancer cell proliferation, migration and invasion in LSCC possibly through the downregulation of miR-204-5p. |
| Pubmed ID | 31114240 |
| Year | 2019 |
| Title | LncRNA MIR100HG Promotes Cancer Cell Proliferation, Migration and Invasion in Laryngeal Squamous Cell Carcinoma Through the Downregulation of miR-204-5p |
External Links
| Links for MIR100HG | GenBank HGNC NONCODE |
| Links for laryngeal squamous cell cancer | OMIM COSMIC |