Basic Information
| LncRNA/CircRNA Name | MIAT |
| Synonyms | MIAT, C22orf35, GOMAFU, LINC00066, NCRNA00066, RNCR2, lncRNA-MIAT |
| Region | GRCh38_22:26646428-26676475 |
| Ensemble | ENSG00000225783 |
| Refseq | NR_003491 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, Western blot |
| Sample | breast cancer tissues, cell lines (MDA-MB-231 and MCF-7 ) |
| Expression Pattern | up-regulated |
| Function Description | MIAT was overexpressed in ER-positive breast cancer tissues and ER-positive breast cancer cell line MCF-7 |
| Pubmed ID | 29792859 |
| Year | 2018 |
| Title | Long non-coding RNA MIAT is estrogen-responsive and promotes estrogen-induced proliferation in ER-positive breast cancer cells |
External Links
| Links for MIAT | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |