Basic Information
| LncRNA/CircRNA Name | MIAT |
| Synonyms | NA |
| Region | GRCh38_22:26646428-26676475 |
| Ensemble | ENSG00000225783 |
| Refseq | NR_003491 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | 2 | ||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | melanoma |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot etc. |
| Sample | melanoma tissue and the adjacent non-tumorous normal skin tissue,cell lines(A375, SK-MEL-28 ,SKMEL-2,HEMaLP and 293 T) |
| Expression Pattern | up-regulated |
| Function Description | Up-regulation of MIAT in melanoma tissue samples and cell lines.MIAT can promote the proliferation and invasion of A375 and SK-MEL-28 cells via targeting miR-150. |
| Pubmed ID | 32300960 |
| Year | 2020 |
| Title | Long non-coding RNA MIAT promotes the growth of melanoma via targeting miR-150. |
External Links
| Links for MIAT | GenBank HGNC NONCODE |
| Links for melanoma | OMIM COSMIC |