Basic Information
| LncRNA/CircRNA Name | AC007271.3 |
| Synonyms | NA |
| Region | GRCh38_2:102172621-102182108 |
| Ensemble | ENSG00000226925 |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | oral squamous cell carcinoma |
| ICD-0-3 | C06.9 |
| Methods | RT-qPCR, Western blot |
| Sample | OSCC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | We identified that AC007271.3 was up-regulated and positively correlated with advanced clinical stage, lymph node metastasis, poor histological differentiation and unfavorable prognosis.Our data indicated that AC007271.3 could promote cell proliferation, invasion and inhibit cell apoptosis of OSCC via the Wnt/?-catenin signaling pathway, which might provide a novel therapeutic approach for OSCC. |
| Pubmed ID | 31759044 |
| Year | 2019 |
| Title | LncRNA AC007271.3 promotes cell proliferation, invasion, migration and inhibits cell apoptosis of OSCC via the Wnt/?-catenin signaling pathway |
External Links
| Links for AC007271.3 | GenBank HGNC NONCODE |
| Links for oral squamous cell carcinoma | OMIM COSMIC |