Basic Information
| LncRNA/CircRNA Name | BANCR |
| Synonyms | BANCR, LINC00586 |
| Region | GRCh38_9:69296682-69311111 |
| Ensemble | ENSG00000278910 |
| Refseq | NR_047671 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, Western blot, in vitro knockdown etc. |
| Sample | cell line (MCF-7, MDA-MB-231, SKBR3, BT-20), breast cancer tissue |
| Expression Pattern | up-regulated |
| Function Description | LncRNA BANCR is highly expressed in breast cancer, which is significantly correlated with the prognosis of patients; moreover, it can promote the growth, invasion and metastasis of ovarian cancer cells. The down-regulation of BANCR can inhibit the proliferation, invasion and metastasis capacities of MCF-7 cells. |
| Pubmed ID | 29565494 |
| Year | 2018 |
| Title | Long non-coding RNA BANCR indicates poor prognosis for breast cancer and promotes cell proliferation and invasion. |
External Links
| Links for BANCR | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |