Basic Information
| LncRNA/CircRNA Name | BANCR |
| Synonyms | BANCR, LINC00586 |
| Region | GRCh38_9:69296682-69311111 |
| Ensemble | ENSG00000278910 |
| Refseq | NR_047671 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | malignant melanoma |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot, in vitro knockdown etc. |
| Sample | malignant melanoma tissues, cell lines (A-375, 1205Lu, UACC903, CHL-1 and sk-mel-5 etc.) |
| Expression Pattern | up-regulated |
| Function Description | BANCR was abnormally overexpressed in human malignant melanoma cell lines and tissues, and increased with tumor stages. The linkage between BANCR and MAPK pathway may provide a novel interpretation for the mechanism of proliferation regulation in malignant melanoma |
| Pubmed ID | 24967732 |
| Year | 2014 |
| Title | Long non-coding RNA BANCR promotes proliferation in malignant melanoma by regulating MAPK pathway activation. |
External Links
| Links for BANCR | GenBank HGNC NONCODE |
| Links for malignant melanoma | OMIM COSMIC |