Basic Information
| LncRNA/CircRNA Name | MEG3 |
| Synonyms | MEG3, FP504, GTL2, LINC00023, NCRNA00023, PRO0518, PRO2160, onco-lncRNA-83, prebp1 |
| Region | GRCh38_14:100779410-100861031 |
| Ensemble | ENSG00000214548 |
| Refseq | NR_002766 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR etc. |
| Sample | breast cancer tissues |
| Expression Pattern | down-regulated |
| Function Description | Our findings revealed that the MEG3 expression was significantly decreased in clinical BC tissues compared to adjacent normal tissues. MEG3 level was significantly associated with differentiation grade, TNM stage and lymph nodes metastasis. |
| Pubmed ID | 28051255 |
| Year | 2016 |
| Title | Down-regulation of long non-coding RNA MEG3 serves as an unfavorable risk factor for survival of patients with breast cancer. |
External Links
| Links for MEG3 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |