Basic Information
| LncRNA/CircRNA Name | BANCR |
| Synonyms | BANCR, LINC00586 |
| Region | GRCh38_9:69296682-69311111 |
| Ensemble | ENSG00000278910 |
| Refseq | NR_047671 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | bladder cancer |
| ICD-0-3 | C67 |
| Methods | qPCR, Cell transfection, Flow cytometry assay, Cell proliferation assay etc. |
| Sample | bladder cancer tissues, cell lines (T24, SW780, SV-HUC-1) |
| Expression Pattern | down-regulated |
| Function Description | BANCR expression levels were remarkably decreased in BC tissues compared with adjacent noncancerous tissues. BANCR expression levels in two BC cell lines were also significantly down-regulated. Clinicopathologic analysis revealed that low BANCR expression was positively correlated with TNM stage, but not associated with other clinicopathological characteristics. Cell proliferation inhibition, apoptosis induction and migration suppression were also observed in pCDNA-BANCR-transfected T24 and SW780 cells. |
| Pubmed ID | 27514530 |
| Year | 2016 |
| Title | Over-expression of long noncoding RNA BANCR inhibits malignant phenotypes of human bladder cancer. |
External Links
| Links for BANCR | GenBank HGNC NONCODE |
| Links for bladder cancer | OMIM COSMIC |